Small vacuum freeze dryer is referred to as small freeze dryer for short. After technical update, the new generation of small freeze dryer simplifies the cumbersome operation of equipment, prevents material pollution and controls material moisture sublimation. It realizes one click start and full-automatic operation, has programmable functions of heating and temperature control, can view the freeze-drying curve, and is convenient for users to observe the freeze-drying process of materials.
For a long time, some users do not know whether to choose food lyophilizer or pharmaceutical lyophilizer when choosing lyophilizer equipment. Freeze dryer is the abbreviation of vacuum freeze dryer. It uses the principle of sublimation to vacuum freeze dry water containing substances to remove water, so that the color, shape and physical structure and activity of substances are basically unchanged. Freeze dryer equipment can be divided into food freeze dryer and pharmaceutical freeze dryer according to the normal use industry.
The food freeze-drying machine is normally used for food freeze-drying, additive freeze-drying, instant powder freeze-drying, traditional Chinese medicine freeze-drying, chemical raw materials freeze-drying and other processing. Pharmaceutical freeze-drying machine is normally used for processing and drying such as drug freeze-drying, cosmetic freeze-drying, biological product freeze-drying, API freeze-drying, biological tissue freeze-drying, blood freeze-drying, probiotic freeze-drying, strain freeze-drying, etc. The technical requirements, configuration requirements, material requirements, sterility requirements and functional requirements of the equipment of the food lyophilizer are different from those of the pharmaceutical lyophilizer.
The design and manufacturing process of the lyophilizer and the selection of parts are directly related to the quality, reliability and service life of the lyophilizer.
In order to make the cooling and heating temperatures of the plate layer uniform, at present, most freeze-drying machine manufacturers use hollow sandwich plate layers with spacer strips inside, which are circulated in the plate layer by temperature transfer intermediate fluid. The old or backward manufacturing method is to make holes on the upper and lower plates or one of the plates, weld the metal plate with the spacer by plug welding, and then machine it. Due to the special working conditions of low temperature, vacuum and even high temperature and pressure of the freeze-drying process, the temperature transfer fluid may leak at the plug welding place after a certain service life. In the vacuum state, the temperature transfer fluid will be atomized instantaneously, resulting in the contamination and scrapping of the freeze-dried products. The new or advanced manufacturing method is that the upper and lower metal plates are not perforated and made with special internal welding equipment, which fundamentally eliminates the occurrence of leakage.
The main efficacy and function of probiotic lyophilized powder is to adjust the balance of human intestinal flora, promote the absorption of nutrients, and enhance the immunity of the intestine and even the whole body. Probiotic lyophilized powder is processed by probiotic lyophilizer using freeze-drying technology. The working principle of probiotic lyophilizer is to sublimate and dry to remove water through the principle of three states of aqueous phase: liquid, solid and gas, which convert or coexist with each other under different temperature and vacuum environment.
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